Invisible Lockpicking Bug
If you are having the invisible lockpicking bug the solution is quite simple, open Fallout4Prefs.ini in your documents (C:\Users\[name]\Documents\My Games\Fallout4\) and under [Display] change:

iSize W=XXXX
iSize H=YYYY
to
iSize W=XXXX-1
iSize H=YYYY-1

For example:
iSize W=1920
iSize H=1080
would be changed to
iSize W=1919
iSize H= 1079

Next do the some for the second Fallout4Prefs.ini located in wherever you insalled steam then steamapps\common\Fallout 4\Fallout 4.

This is a bug that seems to be quite common if you unlock the frame rate and do not vsync it. A thankyou to Vhailor for figuring this one out.

Note: Numerous people are reporting this is not fixing the problem when they play on a 4:3 screen. I sadly can't test this further as I myself don't own or have access to such a monitor anymore. It however has been reported by several players below that lowering the resolution and/or increasing the fov may help (this last part is unconfirmed by myself as I have no way of doing so).


For those with 5:4 screens that run at 1280x1024 resolution. To fix this simply open Fallout4Prefs.ini (located in C:\Users\[name]\Documents\My Games\Fallout4\), then scroll down to the following and change them to the below:
bMaximizeWindow=0
bBorderless=0
bFull Screen=0
iSize H=950
iSize W=1270

Next go to the second Fallout4Prefs.ini located at wherever you installed steam then open steamapps\common\Fallout 4\Fallout4 and make the same changes as previously.

Thankyou Flame_Fury for discovering this 5:4 fix.

This is of course not ideal and I feel for this issue to be entirely resolved will require a patch from Bethesda.