Применять через system.xml (\Documents\Rockstar Games\Red Dead Redemption 2\Settings) с установкой "только чтение".
<graphics>
    <tessellation>kSettingLevel_Ultra</tessellation>
    <shadowQuality>kSettingLevel_High</shadowQuality>
    <farShadowQuality>kSettingLevel_Medium</farShadowQuality>
    <reflectionQuality>kSettingLevel_Medium</reflectionQuality>
    <mirrorQuality>kSettingLevel_Ultra</mirrorQuality>
    <ssao>kSettingLevel_Low</ssao>
    <textureQuality>kSettingLevel_Ultra</textureQuality>
    <particleQuality>kSettingLevel_Ultra</particleQuality>
    <waterQuality>kSettingLevel_Custom</waterQuality>
    <volumetricsQuality>kSettingLevel_Custom</volumetricsQuality>
    <lightingQuality>kSettingLevel_High</lightingQuality>
    <ambientLightingQuality>kSettingLevel_High</ambientLightingQuality>
    <anisotropicFiltering value="4" />
    <taa>kSettingLevel_High</taa>
    <fxaaEnabled value="false" />
    <msaa value="0" />
    <graphicsQualityPreset value="0.500000" />
  </graphics>
  <advancedGraphics>
    <API>kSettingAPI_DX12</API>
    <locked value="false" />
    <asyncComputeEnabled value="false" />
    <transferQueuesEnabled value="true" />
    <shadowSoftShadows>kSettingLevel_Low</shadowSoftShadows>
    <motionBlur value="false" />
    <motionBlurLimit value="16.000000" />
    <particleLightingQuality>kSettingLevel_Low</particleLightingQuality>
    <waterReflectionSSR value="true" />
    <waterRefractionQuality>kSettingLevel_High</waterRefractionQuality>
    <waterReflectionQuality>kSettingLevel_High</waterReflectionQuality>
    <waterSimulationQuality value="2" />
    <waterLightingQuality>kSettingLevel_Ultra</waterLightingQuality>
    <furDisplayQuality>kSettingLevel_High</furDisplayQuality>
    <maxTexUpgradesPerFrame value="5" />
    <shadowGrassShadows>kSettingLevel_Medium</shadowGrassShadows>
    <shadowParticleShadows value="true" />
    <shadowLongShadows value="true" />
    <directionalShadowsAlpha value="false" />
    <worldHeightShadowQuality value="0.330000" />
    <directionalScreenSpaceShadowQuality value="0.330000" />
    <ambientMaskVolumesHighPrecision value="false" />
    <scatteringVolumeQuality>kSettingLevel_Medium</scatteringVolumeQuality>
    <volumetricsRaymarchQuality>kSettingLevel_Low</volumetricsRaymarchQuality>
    <volumetricsLightingQuality>kSettingLevel_Medium</volumetricsLightingQuality>
    <volumetricsRaymarchResolutionUnclamped value="false" />
    <terrainShadowQuality>kSettingLevel_Medium</terrainShadowQuality>
    <damageModelsDisabled value="false" />
    <decalQuality>kSettingLevel_High</decalQuality>
    <ssaoFullScreenEnabled value="false" />
    <ssaoType value="0" />
    <ssdoSampleCount value="4" />
    <ssdoUseDualRadii value="false" />
    <ssdoResolution>kSettingLevel_Low</ssdoResolution>
    <ssdoTAABlendEnabled value="true" />
    <ssroSampleCount value="2" />
    <snowGlints value="true" />
    <POMQuality>kSettingLevel_High</POMQuality>
    <probeRelightEveryFrame value="false" />
    <scalingMode>kSettingScale_Mode5o4</scalingMode>
    <reflectionMSAA value="0" />
    <lodScale value="0.900000" />
    <grassLod value="2.000000" />
    <pedLodBias value="0.000000" />
    <vehicleLodBias value="0.000000" />
    <sharpenIntensity value="2.000000" />
    <treeQuality>kSettingLevel_High</treeQuality>
    <deepsurfaceQuality>kSettingLevel_Ultra</deepsurfaceQuality>
    <treeTessellationEnabled value="false" />
  </advancedGraphics>
  <video>
    <adapterIndex value="0" />
    <outputIndex value="0" />
    <resolutionIndex value="14" />
    <screenWidth value="1920" />
    <screenHeight value="1080" />
    <refreshRateIndex value="1" />
    <refreshRateNumerator value="60" />
    <refreshRateDenominator value="1" />
    <windowed value="0" />
    <vSync value="0" />
    <tripleBuffered value="true" />
    <pauseOnFocusLoss value="false" />
    <constrainMousePointer value="true" />
  </video>