I have a 64 bit LInux installation running the Linux SMP2 client and a PC-BSD installation running the 64 bit Linux client in a VirtualBox.
32 bit Linux users have not been able to participate in the SMP2 program since a 64 bit OS was needed to coordinate work between the two cores running the 32 bit Gromacs application. The Windows 6.3 beta client does work very well under Wine and does not require a 64 bit OS. I have setup a installation under Vector Linux and it seems to produce more points on the same machine than a 64 bit Linux installation running SMP2. Early results are encouraging.

These are the instructions that I posted on the Vector Linux forums. Minor changes would be needed for other Linux Distributions.

Step 1 - Install wine and cabextract if they are not already installed.
Step 2 - run winecfg to set up your basic parameters
Step 3 - Go the folding@home web page and get a passkey. This is necessary for the bonus points.


Step 4 - Open a hole in your firewall to allow the folding@home application to reach the application server. This is port 8080.
Use VASM in Super User Mode to Network to Firewall to Open ports. Open port 8080 in the list.

Step 5 - Download the new 6.30 Windows SMP client from the Folding@home Windows high performance clients page.


Create a directory to put the executable in. Change the permissions on the file to run as a program either through your file browser or in a terminal. You can change the program name to something shorter than Folding@home-Win32-x86.exe. I use fah6.exe.

In a terminal, navigate to the folder where the program is and do
wine fah6.exe -smp 2 -configonly
Be sure to select "big" work units in your preferences.

After you have done the configuration, run it in a terminal.

wine fah6.exe -smp 2 -forceasm -bigadv -advmethods -verbosity 9

Of course if you have more than two cores, use -smp 4 or if you want to keep one core free for your own use, use -smp 3.